swiss albino mice strain

swiss albino mice strain

The strains were maintained on Sabouraud agar plus yeast extract (SAB + YE) slants, at room temperature (28 +/- 1C). This virus produced symptoms of irrita-bility and involvement of the central nervous system in these mammals. Experiments were carried out on healthy adult male albino mice of the Swiss albino strain weighing between 15-20 gm. A total of 18 healthy male Swiss albino mice which were 4 weeks old, weighed from 16 to 18 grams were provided by the Experimental Animal Breeding Service, Vietnam Medical Military University. Swiss albino mice-----31 Table 5. Mice were received at RBU 3, Taconic Biotechnology, Albany NY and acclimated for three days on irradiated NIH #31M rodent diet and sterilized water ad lib, sterile contact bedding (paper chip) and a 12:12 . 10.55. strain was freshly isolated from oropharyngeal secretion of an AIDS patient (strain 18) and presented low phospholipase (Pz=0.482) and proteinase (0.780 U.mL-1) activity.

Mice of various strain were given orally eggs of Hymenolepis nana maintained by ddY mice and sacrificed for the adult wormrecovery 2 weeks after the administration of the eggs. Test material is applied topically, daily on four consecutive days. Author information: H&E, 100 . The second group was given oral dose equivalent to 1/10 LD50 (14 mg/kg b.w.) A quantity of twenty mice (ten males and ten females) was submitted for testing, strain identified as Line ICR (IcrTac:ICR), age 7 weeks. A total of 54 albino mice (Swiss strain) weighing 25-30 g were allocated to each experimental model and in each model there were three groups. Characteristics

Carries a Mus musculus domesticus -origin Y chromosome (Tucker et al, 1992). I. Automated Quantification and Topographical Distribution of the Whole Population of S- and L-Cones in Adult Albino and Pigmented Rats . Four to six weeks old inbred mice of Swiss Albino strain of either sex weighing 25-30 g were selected, and kept in well ventilated polypropylene cages under standard conditions of temperature (23 2C), humidity (50 5%) and light (10 and 14 h of light and dark, respectively). All of the Swiss albino mice that received PAF died within 15-20 min, whereas none of the C57BL/6J or BALB/c mice injected with PAF died.

These strains were genetically modified to express individually Cry1Aa, Cry1Ab, Cry1Ac or Cry2A, and bioassays using the purified proteins from these genetically modified (GM) Bt. The widely distributed Swiss albino mice, largely noninbred, are mainly derived from two males and seven females which Clara J. Lynch of the Rockefeller Institute obtained from A. de Coulon of Lausanne in 1926 (Lynch, 1961, personal communication). Female mice were selected nulliparus and non-pregnant. However, if. The mice were housed under standard laboratory conditions of light/dark cycle for 12 h at temperature 27 2C in the animal house situated at the Department of Biochemistry, University . H&E, 400 . Swiss being an outbred animal, is suitable for toxicology as it has variability between animals. Swiss albino mice-----31 Table 5. route and organs of inoculated animals examined for virus content and histopathological . Because they're easy to breed, virtually all are the same, & because they . Within strain, the increase in weight due to HFD was statistically significant starting from week 2 onwards in the Swiss mice, and from week 3 in the B6 mice (P < 0.05) compared to controls. chloroquine sensitive Plasmodium berghei ANKA strain. Origin: Swiss albino mice from the City of Hope Medical Centre, California. Specifically, for wild house mice, Mus musculus, the LD 50 is reported as 32.7 mg/kg body weight, while for Swiss Webster albino mice, an outbred strain of laboratory mice, the value is 54 mg/kg body weight (Li & Marsh 1988) though Bell reported a value of 25 mg/kg for white mice. . Shaikh Shahinur Rahman, Mohammad Ayub Ali, Mohammad Nazibur Rahman. Hematology and Clinical Chemistry - Male Non-Swiss Albino.

Acute and sub acute toxicity studies of the extracts were carried out in Swiss albino mice prior to antimalarial activity test. The aim was to evaluate the analgesic activity of perindopril in chemical, thermal and mechanical pain on Swiss albino mice. This was systematically recognized and Swiss mice adopted as a model. Albino rats are easily distinguished due to their white coats and pink eyes. Swiss albino mice Mus musculus is a widely used mouse strain, which is used for many research investigations due to its small size, short life span, and easy maintenance. All the immunized BALB/c mice failed to generate neutralizing antibodies against the New Guinea C laboratory (NGC-lab) strain of dengue virus type 2. Nagasawa H, Yanai R, Taniguchi H, Tokuzen R, Nakahara W. J Natl Cancer Inst, 57(2):425-430, 01 Aug 1976 Cited by: 34 articles | PMID: 187774 Automated Quantification and Topographical Distribution of the Whole Population of S- and L-Cones in Adult Albino and Pigmented Rats . Antimalarial activity of aqueous extract of seeds of D. angustifolia . Swiss albino mice of both genders obtained from the animal Beige and hairless mice were comparatively resistant to penetration since only 60 and 30% respectively of these hosts had at least 90% of the cercariae penetrating. Open Access Library Journal Vol.2 No.11 November 13, 2015. A total of 45 adult male swiss albino mice strain Musmusculus domestic were used in the experiment animals were divided into three groups (each of 15 mice ) .The first group was served as control group, and received 0.2 ml of distilled water. Females are excellent mothers and produce litters with an average of 14 pups. Sprague-Dawley and Wistar are the main rat strains.

Distribution of melanopsin positive neurons in pigmented and albino . were used. Mice can be genetically manipulated to mimic virtually any human disease or condition.

The mice and rats were allowed to adapted for 15 days before study. FIGURE 7.Cavity lined by ciliated cuboidal epithelium (arrows). In whole-mounted retinas from pigmented C57/BL6 and albino Swiss mice, the longwave-sensitive (L) and the shortwave-sensitive (S) opsins were immunodetected to analyze the population of each cone type. Then, the 5 g doses of PAF were intraperitoneally injected into 3 strains of mice: Swiss albino, C57BL/6J, and BALB/c (n = 6 per strain). It is not often used in R&D studies. Why is Swiss albino mice used for testing genotoxicity? Maintenance of mice stock is an essential need for research facilities due to their widespread use in clinical studies related to biomedical research. Wiki User. tion in Swiss albino strain of mice as no such reports on this strain has been foundtill date. Importance of mice as a . Selected for high early mammary tumour incidence with full-sib mating starting in 1964, and F20 in 1972.

The present study explores mice's genetic background on disease stability and severity induced by IMQ. Male Swiss albino mice, 5-7 weeks of age and 23-38 gm of weight were obtained from the Ethiopia Health and Nutrition Research Institute (EHNRI). Effects of Mixed Dietary Fats on the Distribution of Triglycerides in Different Tissues of Exercised Trained Swiss Albino Mice. BALB/c is an albino, immunodeficient laboratory-bred strain of the house mouse from which a number of common substrains are derived. Swiss mice are highly resistance to Leishmania infections in concordance with observed response in humans. SWR/J mice are used widely in research as a general purpose strain. Hsd:ND4~ND4 Swiss Webster outbred mice~ND4 Swiss Webster outbred mouse~outbred mice~outbred mouse~Albino~ND4~Swiss Webster~Swiss~032. The MTD was of variations in the gender, strains and species specific then verified in a larger group of animals (n=10) which detoxification processes [11-14]. b: Section of kidney of 500mg/Kg bw of P. niruri treated . They also have pink eyes, instead of the usual red or black. Hamsters and mice were challenged intracerebrally and hamsters rectally with 14 strains of rabies street virus in order to determine the better species of animal and route of inoculation . The strains were maintained on Sabouraud agar plus yeast extract (SAB + YE) slants, at room temperature (28 +/- 1C). SWR/J mice are highly susceptible to experimental allergic encephalomyelitis. spore-crystals have been published [26]. The mice were monitored for survival for up to 6 days. Swiss albino mice was found to be 110 mg/kg BW by 2. The ear of the albino mouse has been proposed as an alternative test system. Hairless mice gave the best average worm recovery (23%) and parasite maturation (53%) and beige the poorest . JAX Swiss Outbred mice are an albino outbred stock (Swiss/ICR-derived from ARC) which produces large litters and may be useful in toxicology and pharmacology screens. Animals and experimental design. The mice have been maintained as a closed colony since 1951. Envigo uses well-established techniques to successfully produce time mated rats, mice, hamsters, and rabbits. Experimental animals: 36 Swiss albino mice (weight 20-25 g) and 30 Wistar rats (weight 180-200 g) were procured from LACSMI Biofarm Pvt. . The specificity of PAF-induced death in Swiss albino mice was further confirmed with 2 sets of experiments: (1) by pre-injecting the mice with 2 structurally unrelated, yet specific, PAF-R antagonists, namely BN-52021 and WEB-2086 (20 mg/kg body wt) and (2) by increasing the level of circulating PAF-AH by pretreating the mice with rPAF-AH. 2010-03-25 23:50:56. Antimalarial activity of aqueous extract of seeds of D. angustifolia .

Genet. Now widely used in research as a general-purpose strain. As new strains . of the testis in the Swiss Albino strain of mice, which FIGURE 8.Duct lined by keratinized stratified squamous epithelium. Taconic received the Swiss Webster outbred model from the Rockefeller Institute through Rockland Farms, Inc. in 1940. of dimethoate Rabies Street Virus Strains in the Syrian Hamster and in the Swiss Albino Mouse - Reginald L. Reagan, William C. Day, A. L. Brueckner, 1952 . Ni was administered orally on body weight base from days 6 to 13 of gestation period. Females may be used as recipients for non-albino embryo transfers. Developing a model that shows characteristics of both strains was proposed involving a cross-breed between BALB/c and Swiss mice. The original stock probably came from Paris. Number and Distribution of Mouse Retinal Cone Photoreceptors: Differences between an Albino (Swiss) and a Pigmented (C57/BL6) Strain. 2. Details: Robust mouse; Large litters (average 10.7 pups per litter) Males may become agressive after 7 . Model information sheet - EU. E. coli lacking BLP are less toxic than the parental strain with BLP in Swiss albino mice. Swiss Albino is usually used in toxicology studies. Laboratory mice were inoculated with 3 different strains of Rift Valley fever virus (RVFV): namely, the prototype, the Nigerian, and the Lunyo variant strains of RVFV. FIGURE 6.Skeletal muscle tissue surrounded by sheet of anaplastic cells. Two hundred and twenty four female swiss albino mice (Mus musculus) were used. 'Swiss' mice from Lausanne, inbred at the Rockefeller Institute from about 1926 (Lynch, 1969). administration of -cyfluthrin to Swiss albino mice for 21 days recorded a significant decline in body weight of -cyfluthrin treated . 6H 2 O) to Swiss albino mice fetus. Origin: Derived from animals from Swiss Webster stock derived by the University of Notre Dame, Notre Dame, Indiana. Two-way selection of a stock of Swiss albino mice for mammary tumorigenesis: establishment of two new strains (SHN and SLN). N:NIH Swiss outbred mice (albino) were crossed to C57BL/6N (black, non-agouti) mice to generate a hybrid black mouse that was heterozygous for the agouti locus. Introduction Teratology is a branch of Embryology that deals with abnormal development . Teratological experiments was started from 1820s with the studies of . A transient decrease in BW gain was observed in IMI oral route.

On day 18 of gestation, uteri of the sacrificed dams were examined. SPF stock originally obtained from Animal Resource Centre (ARC), Western Australia 1996. or i.p. USD. DOI: 10.4236/oalib.1102113 670 Downloads 1,083 Views. Best Answer. Animals. Hematology and Clinical Chemistry - Female Non-Swiss Albino. route and organs of inoculated animals examined for virus content and histopathological . Experiments were carried out on 200 male Swiss strain albino mice, 6-8 weeks old. Based on genotype analysis using microsatellite markers, SL/Kh was defined as a recombinant congenic strain between proto-SL and AKR strain mice. Healthy male albino mice (Swiss strain) weighing between 19 and 23 g were obtained from Nigerian Institute of Medical Research (NIMR), Lagos State, Nigeria. FIGURE 5.Mitotic figures in the rosettes . and kept in our animal facility for 7 days, on animal food and water ad libitum, for deworming and acclimatization in a controlled condition of room temperature, humidity (50 percent RH), and light (12 hr:12 hr light dark period). To understand the relative contribution of BLP in inducing lethality, we intraperitoneally injected 1 . The mice were derived by caesarean from randomly chosen breeders and reintroduced into a Barrier Nucleus Expansion Colony in 1965-1969. The original group of Swiss mice that served as progenitors of this stock consisted of two male and seven female albino mice derived from a non-inbred stock in the laboratory of Dr. de Coulon, Centre Anticancereux Romand, Lausanne, Switzerland. Predominant characteristics 1. Some Albino Mice Strains are Inbred In addition, study compared serum interferon gamma (INF-) and interleukin-4 (IL-4) levels between the SAB mice, Swiss albino and BALB/c mice. Experiment 1 Method Fifty nulliparous Rockland-Swiss (R-S) albino mice (Mus musculus), 60-65 days of age, selected from a population maintained as an outbred strain in a closed colony, were housed individually in 28 x 1 8 x 13-cm translucent cages, the floors of which were covered with pine shavings. The development of an organism is a complex process of embryogenesis involved cell .

These various strains and stocks each have different characteristics and natures that make them useful for different areas of study. As mouse has been considered as a prime organism of choice for modeling human diseases, many inbred strains of mice have been described providing a wealth of di erent genotypic and phenotypic information for genetic and other studies. The mice were divided into 2 groups: group 1 (control group) and group 2 (study group) with 9 mice per each group. United States - 202A - Indianapolis, IN. Laboratory mice were inoculated with 3 different strains of Rift Valley fever virus (RVFV): namely, the prototype, the Nigerian, and the Lunyo variant strains of RVFV. Carworth Farm selected one line of mice for its vigour and productivity (1935). High level of cholelithiasis (gallstones) (Khanuja et al, 1995). According to the Institutional Animal Ethical Committee of Rajiv Gandhi University, mice were maintained in the animal facility. Opsin immunodetection in pigmented (C57/BL6) and albino (Swiss) mouse strains. The mice and rats were kept at temperature of 252 C and RH of 50-60% under 12 hr light and dark cycle. Misima. Swiss (Arc:Arc(S)) mice; Strain description: Outbred mice: Coat colour: Albino: Source of colony: Re-derived into the SPF Barrier Dec 2003 from LAS stock.

To determine whether immune protection was activated by immunization with the RH:NPT1 strain, distinct genotype strains of T. gondii were employed to infect the immunized mice. Behavioral changes, mortality, weight loss, reduction in . The NCS strain of Swiss mice was used in all phases of the study (Nelson & Collins, 1961). In addition, we determined the specificity of neutralizing antibodies elicited in 3-week-old Swiss albino mice against two homotypic dengue-2 strains, i.e., NGC-lab and Singapore 1999 (SING/99). Swiss albino mice Mus musculus is a widely used mouse strain, which is used for many research investigations due to its small size, short life span, and easy maintenance. Copy. You searched for: Publication year rev 7978-2022 Remove constraint Publication year rev: 7978-2022 Publication Year 2022 Remove constraint Publication Year: 2022 Subject albino Remove constraint Subject: albino Five male an 5d female . The animals were approximately 8 weeks old and weighed 25-30 g. We purpose here to analyze and compare the population and topography of cone photoreceptors in two mouse strains using automated routines, and to design a method of retinal sampling for their accurate manual quantification.

Coat: Albino. Me49 strain was maintained by oral inoculation of Swiss albino mice each with 20 cysts obtained from brains of previously infected mice 60 . Aging mice exhibit a high incidence of lung and mammary gland tumors. Female animals were obtained when 5-6 weeks old and used They were kept in the animal care facility of the Aklilu Lemma Institute Pathology, Addis Ababa University, for one week prior to the initiation of the . They are a direct descendant of the Norway rat, as almost every rat breed is, but, due to genetic modification, they have pure white hair instead of having color. Black Swiss Mouse Details Developed at the NIH Genetic Resource by Dr. Carl Hansen. A total of 45 adult male swiss albino mice strain Musmusculus domestic were used in the experiment animals were divided into three groups (each of 15 mice ) .The first group was served as control group, and received 0.2 ml of distilled water. Retired breeder. Based on LD 50 , Ni doses (46.125, 92.25, and 184.5) mg Ni/kg b.wt. The Jackson Laboratory, Charles River Laboratories, Taconic Biosciences, and Harlan Laboratories are the main suppliers. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation. Animals were inoculated with either infective mouse brain or serum by the i.c. the Swiss Albino mice.

Animals Two hundred and twenty four female swiss albino . The animals were acclimatized for 2 weeks before starting the experimental procedures. Acute and sub acute toxicity studies of the extracts were carried out in Swiss albino mice prior to antimalarial activity test. You could also compare C57BL/6 (WT) with Foxp3sf (scurfy mice who have a deletion in the forkhead domain of Foxp3, fail to develop thymic-derived Foxp3+ regulatory T cells/ nTreg). After chronic exposure to P. berghei NK65 strain, the level of parasitemia was assessed. . . Download scientific diagram | a: Section of control mice kidney showing normal glomeruls, proximal tubules (PT) and distal tubules (DT). Methods: Three distinct strains of mice (Balb/c, C57BL/6, and Swiss albino) were divided into four groups (Vaseline, IMQ, IMQ+Clobetasol, and IMQ+Curcumin). Inst. C57BL/6 and BALB/c are the main mouse strains. Flat mounted left retinas from a pigmented (A,B) and an . The strain was created from 2 outbred albino males and 7 outbred albino females originating from the "Centre Anticancreux de Romand" (Lausanne, Switzerland) and imported to the Rockfeller Institute by Lynch (1926). 1) of the 68th rabbit passage has been successfully transmitted to Swiss albino mice and carried through ten passages in this species by intracerebral inoculation. Infection in immunosuppressed outbred mice Ten mal ane d 10 femal e Swiss albino mice were immunosuppressed with corticosteroid beginning 1 day prior to infection. Psoriasis area . These animals were maintained in the animal house of Devaki Amma Memorial College of Pharmacy, Chelembra, Malappuram, Kerala, India.

Number and Distribution of Mouse Retinal Cone Photoreceptors: Differences between an Albino (Swiss) and a Pigmented (C57/BL6) Strain. The ability of protection against acute infection was . They also develop extreme polydipsia and polyuria (nephrogenic diabetes insipidus) with increasing age. JAX Swiss Outbred mice are an albino outbred stock derived from a Swiss/ICR-derived stock from the Animal Resources Centre (ARC) in Australia.

The second group was given oral dose equivalent to 1/10 LD50 (14 mg/kg b.w.) The control group received norma In whole-mounted retinas from pigmented C57/BL6 and albino Swiss mice, the longwave-sensitive (L) and the shortwave-sensitive (S) opsins were immunodetected to analyze the .

H&E, 100 . Mice are considered to be a similar model to humans in the pathogenesis of malaria. or i.p. 034608 - JAX Swiss Outbred Strain Details If you need help with your order, contactCustomer Support For in-depth product & services help, ask ourTechnical Information Scientists Swiss albino mice of LACA strain were purchased from the Directorate of health services, Shillong, India. A strain, in reference to rodents, is a group in which all members are as nearly as possible genetically identical.In laboratory mice, this is accomplished through inbreeding. 3. CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): SUMMARI': The 'B ' virus (strain no. us. A summary and overview of the mice and rats used in biomedical research, based on a survey of formal publications. Strain description: SL/Kh is a member of the spontaneous leukemia family of mice, originated from outbred Swiss albino mice. Tuberculous morbidity in Swiss albino mice inlmunized with BCG* BY RICIIARD COSTELLO AND SARA C. SLATS The Rockefeller Unteersity, New YorAc, New York 10021 (Recezeed 8 Jqbne 1970) . United States - 237 - Livermore, CA. Distribution of melanopsin positive neurons in pigmented and albino . Weekly collection of faeces for 11 weeks and subsequen post mortemt .

The mice of ddY, ICR, C3H and BALB/C were highly susceptible to the eggs while . Animals were inoculated with either infective mouse brain or serum by the i.c. They were purchased from the animal house of the Medical Parasitology Department, Faculty of Medicine, Alexandria . Inbred as SWM/Ms by Natl. of dimethoate However, this model is sensitive to the genetic variation of mice. Differential dengue cross-reactive and neutralizing antibody responses in BALB/c and Swiss albino mice induced by immunization with flaviviral vaccines and by infection with homotypic dengue-2 virus strains. A Preliminary Study on Susceptibility of Mice of Various Strain to Hymenolepis nana Eggs. The objective of the present study was to investigate and compare the susceptibility of the SAB mice, the Swiss albino and BALB/c mice (SAB) to L. donovani infection. Healthy, adult, pathogen free, colony bred male albino mice (Mus musculus) of Swiss strain weighing between 30-40 gm were obtained from IAEC registered supplier Cadila Pharmaceuticals, Dholka, Gujarat, . Laboratory mice are the same species as the house mouse; however, they are often very different in behaviour and physiology.There are hundreds of established inbred, outbred, and transgenic strains. Lim CS (1), Chua JJ, Wilkerson J, Chow VT. As originally proposed by the author, the test was performed as follows: Ten microliters (liquid) or 10 mg (solid paste) is applied to the dorsal aspect of one ear; the other ear serves as a control. Maintenance of mice stock is an essential need for research facilities due to their widespread use in clinical studies related to biomedical research. 10 mice of each group was challenged with 1 10 3 tachyzoites of RH or PYS at 42 days post-immunization. The offspring are scattered around the world. The mice of group 2 Albino mice of Swiss strains were used for the pharmacological and toxicological activity. Experimental animals and parasite strain. This study evaluates the effect of parenteral antimalarials on the spleen and liver of Swiss albino mice after chronic exposure to Plasmodium berghei. chloroquine sensitive Plasmodium berghei ANKA strain. To the best of our knowledge, the present treated animals . Animals were allowed food and water ad libitum. as well as strain differences. Mice are the most commonly used animal model for studying human disease, and for many good reasons: Mice are biologically very similar to humans and get many of the same diseases, for the same genetic reasons. Behavioral changes, mortality, weight loss, reduction in . October 23, 2021 by Andreea Juganaru. As yet, response of the cross- Some common strains of albino mouse used in labs are: BALB/c, CD-1, CB17 SCID, A/J mice, and ICR mice. Key Words: Retinoids, Teratological, Swiss albino mice, Skin. Study now. Similarly, 5 male mice of each strain were infected percutaneously with 500 larvae. Ltd. Pune, India. Fighting mice data sheet. Cite 9th Jul, 2019 Female mice weighing about 25-30 g were used for the study. Of the other strains the Swiss albino strain most resembled strain C3H.

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